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Need To Know > World > Three men contract same symptom of flesh-eating bug in their EYES
A rare flesh-eating infection left three men with swollen eyelids, with one tragically dying, as doctors emphasize early aggressive treatment to prevent fatal outcomes.
World

Three men contract same symptom of flesh-eating bug in their EYES

Amy Walters
Last updated: March 19, 2025 8:53 am
Amy Walters Published March 19, 2025
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A and B: Postoperative result at 3 weeks postoperatively. (Jam Press/Science Direct)
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A rare flesh-eating bug has seen three men suffering similar symptoms – leaving one dead.

The patients, aged 47, and 81, are believed to have contracted the disease in different ways.

However, they all suffered similar physical reactions including swollen eyelids, reports Need To Know.

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The first patient, aged 65 years old, was diagnosed with streptococcus pyogenes after his left eyelid began to swell.

A rare flesh-eating infection left three men with swollen eyelids, with one tragically dying, as doctors emphasize early aggressive treatment to prevent fatal outcomes.
WARNING: GRAPHIC CONTENT. Findings at presentation to our emergency department. Note the necrotic lesion (arrows) on the upper medial canthus. (Jam Press/Science Direct)

He was taken to the emergency department following a referral with tension in the eye, coupled with vomiting and nausea.

The affected organ showed signs of hyperthermia and blood secretion without pus.

After a swab was taken, the patient was hospitalised for a course of antibiotics, before his temperature skyrocketed.

Overnight, he developed white lesions around the eye and was rushed into surgery.

A rare flesh-eating infection left three men with swollen eyelids, with one tragically dying, as doctors emphasize early aggressive treatment to prevent fatal outcomes.
WARNING: GRAPHIC CONTENT. A) Situs during surgery after debridement of necrotic tissue and insertion of antibiotic pellets and at the end of surgery with drainages inserted (B). Vital skin was spared during debridement. (Jam Press/Science Direct)

Necrotic tissue was found in the eye as well as in his nose and neck.

Sadly, the patient developed a multi-drug-resistant bacteria and passed away within two weeks.

The second patient, aged 47, also presented with a swollen left eyelid after hitting his head the day before.

A rare flesh-eating infection left three men with swollen eyelids, with one tragically dying, as doctors emphasize early aggressive treatment to prevent fatal outcomes.
WARNING: GRAPHIC CONTENT. Situs at the end of surgery with multiple drainages inserted. (Jam Press/Science Direct)

Luckily, after multiple surgical revisions, doctors were able to remove all necrotic tissue.

A week later, he was in the all-clear.

The third patient, an 81-year-old man, was reported to have had a sudden swelling of his left eyelid, coupled with discolouring.

The cause is unknown.

After all dead tissue was removed, the patient was able to walk away without any major disfigurement and good lid function.

A rare flesh-eating infection left three men with swollen eyelids, with one tragically dying, as doctors emphasize early aggressive treatment to prevent fatal outcomes.
WARNING: GRAPHIC CONTENT.
Initial presentation of case 2 with marked swelling of the left upper eyelid and purple-colored discoloration (arrows) of the skin at the medial upper eyelid. (Jam Press/Science Direct)

The rare flesh-eating condition is known as periorbital necrotizing soft tissue infection (NSTI), and is caused by either polymicrobial infection (type 1) or streptococcus pyogenes and/or staphylococcus species (type 2).

The three cases were presented in a medical journal earlier this year.

A rare flesh-eating infection left three men with swollen eyelids, with one tragically dying, as doctors emphasize early aggressive treatment to prevent fatal outcomes.
WARNING: GRAPHIC CONTENT. (A) Clinical presentations prior to first surgery with overtly necrotic tissue . (B) Note the whitish lesion at the lower medial canthus. (Jam Press/Science Direct)

“Based on the negative experience with our first case, we developed a more aggressive surgical plan for cases with periorbital NSTI,” reads an extract of the report by lead author Isabella D. Baur from the University Eye Clinic Augsburg in Germany.

“After early debridement, the patient is surgically reevaluated on a daily basis until surgery is deemed to have been unnecessary.

A rare flesh-eating infection left three men with swollen eyelids, with one tragically dying, as doctors emphasize early aggressive treatment to prevent fatal outcomes.
WARNING: GRAPHIC CONTENT.
Final result three weeks after wound closure with a free skin graft. (Jam Press/Science Direct)

“:We follow this approach, as necrotic tissue is sometimes identified intraoperatively from a lack of resistance to manipulation rather than from its clinical aspect alone.

“At a later point, plastic surgery may be required when the infection is under control.”

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